#1 Voted Med-Aesthetics Clinic

Polynucleotides treatmentin Malta

ARE YOU LOOKING TO RESTORE FIRMER, SMOOTHER, MORE RADIANT SKIN?

Polynucleotides (Salmon DNA) boost hydration, repair damaged skin, and stimulate collagen, giving you smoother texture, improved elasticity, and a naturally refreshed glow.

  • 1ml from €249
4.9 · 500+ verified client reviews
Procedure Time2-3 hours
Downtime2 weeks, with doctor monitoring
Results Last For6-12 months
Results Visible Inimmediate
AnaestheticLocal anesthetic
Polynucleotides treatment in Malta | Salmon DNA Skin Treatment, Carisma Aesthetics Malta
Doctor-led
30+years in wellness
#1 Voted Clinic Malta Healthcare Awards

Polynucleotides results

Crepey eye area skin, Before photo (result 1 of 10)
Crepey eye area skin, After photo (result 1 of 10)
Crepey eye area skinMarija C.“The crepey skin by my eye sits firmer now and the little lines across my cheek are much harder to spot.”

The real reason people book

Your skin looks tired and depleted, even when you feel well

Polynucleotides work deep in the skin to rebuild hydration and collagen from within, so your complexion looks healthier, brighter, and refreshed, in a way that is unmistakably you.

Natural Confidence Guarantee

Every plan starts with a doctor-led skin assessment and a natural-first approach that supports your skin's own repair, never overdone, backed by a complimentary review until you are 100% satisfied with a result that still looks like you.

Doctor-led

Assessment first

Never a salesperson

Natural-first

Skin from within

We regenerate, never overfill

100%

Satisfaction

Free follow-up until you are happy

Book Your Free Consultation4.9 · 500+ verified client reviews

precision areas of refinement

This regenerative treatment stimulates cellular renewal at the deepest level. Below are the primary zones of application.

Face
Face

Full Face

Activates fibroblast renewal across the face for improved texture, tone, and radiance over time.

Eyes
Eyes

Under-Eye Area

Targets the delicate periorbital skin where dark circles, crepiness, and thinning are most visible.

Neck
Neck

Neck

Stimulates collagen regeneration in the neck where skin quality declines earlier than expected.

Hands
Hands

Hands

Renews the thin, exposed skin on the hands for a more hydrated, even-toned appearance.

Your practitioner will assess which zones will benefit most during your initial consultation.

Decolletage, forehead, inner arms, lip area, acne scarring zones, scalp

Is this treatment for you?

Is this suitable for you?

Polynucleotides work at a cellular level to regenerate and rejuvenate skin from within. This is a treatment for those who value long-term skin health over instant visual change. Results build gradually with each session.

Designed for

  • The tired, depleted complexionYour skin looks dull, dehydrated, and lacklustre, it has lost the bounce and glow it once had.
  • The delicate under-eyeCrepey, thin, shadowed skin around your eyes makes you look more tired than you feel.
  • The long-term skin investorYou care about real skin health over a quick fix, and want a science-led result that builds and lasts.

May not be ideal if

  • You want to see the full result from a single session, skin renewal builds gradually over your course
  • You are looking to restore volume or reshape features, that is what dermal fillers are for, and we are happy to guide you
  • You are pregnant or breastfeeding, we will warmly welcome you back afterwards
  • You have an active skin infection in the area, we will treat once your skin has settled
  • You take blood-thinning medication, let us know first so we can plan your treatment safely

Your treatment experience

Step 1
Consultation & Skin Assessment

Consultation & Skin Assessment

We assess your skin condition, concerns, and medical history with one of our doctors, then design a regenerative plan tailored to you.

Step 2
Targeted Treatment

Targeted Treatment

Your doctor delivers the polynucleotide solution through fine, precise injections, comfortable, controlled, and with minimal downtime.

Step 3
Ongoing Review & Renewal

Ongoing Review & Renewal

Your doctor monitors how your skin responds across your course and refines the plan to support natural, lasting renewal.

Malta's trusted clinic for salmon DNA

As featured in Times of Malta · Lovin Malta · Bay · Malta Daily · Malta Today

  • medically qualified practitioners

    Every salmon dna treatment is performed by a qualified doctor.

  • Advanced Facial Anatomy Expertise

    Precision salmon dna techniques tailored to your unique facial anatomy.

  • Personalised Treatment Plans

    Your salmon dna plan is designed to enhance, never overcorrect.

  • Clinically Approved Products

    Clinically Approved Products, CE-marked, clinically approved salmon dna and evidence-based protocols.

the carisma difference

Malta’s #1 leading wellness chain

our commitment

  • Natural, refined salmon dna results, never overdone, never frozen
  • Doctor-led treatments with advanced facial anatomy expertise
  • Safe, ethical care using clinically approved products
  • A personalised journey from consultation to aftercare

WHY MALTA CHOOSES Carisma for salmon dna

  • Created by the team behind Malta’s leading spa and medical aesthetics centres
  • Doctor-led salmon dna treatments with a focus on safety and long-term results
  • A personalised journey from consultation to aftercare
  • Seamless experience with ongoing support and guidance
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Complimentary On-Site Parking

Preparation & Aftercare

Your session, step by step

A smooth polynucleotides experience begins with a few simple steps. Here is what to know before, during, and after your session at our Malta clinic.

BeforeBefore

Simple preparation supports the best response.

  • Discuss skin goals and treatment history
  • Disclose medications and active skin conditions
  • Avoid blood thinners and alcohol for 24 hours
  • Arrive with clean, makeup-free skin
DuringDuring

Precise delivery targets deep skin renewal.

  • Injection sites are carefully mapped
  • Fine needles deliver the polynucleotide solution
  • Mild pinching may occur; numbing can be applied
  • Session takes 20–30 minutes
AfterAfter

Gentle care supports the bio-stimulation process

  • Minor redness resolves within 24–48 hours
  • Avoid makeup and active skincare for 12 hours
  • No intense exercise or heat for 24 hours
  • Skin quality improves progressively over 3–4 weeks
BOOK YOUR FREE CONSULTATION4.9 · 500+ verified client reviews

Your polynucleotides plan

Malta's Doctor-Led Polynucleotides Plan

Doctor-Led Precision

Every treatment is performed by a medically qualified doctor, never a salon, never nurse-only.

Natural Skin Renewal

Polynucleotides rebuild hydration and collagen from within, your skin looks healthier and refreshed, never altered.

Progressive, Lasting Results

Results build across your course and can last 6 to 12 months, supported by a personalised maintenance plan.

  • Free doctor-led skin consultation
  • Personalised, medically guided treatment plan
  • Expert polynucleotide (Salmon DNA) treatment (from €249)
  • Progress review across your course
  • Aftercare guidance & ongoing support

From €249 per ml

Book Your Polynucleotides Appointment
★★★★★500+ verified reviews

Frequently asked questions

Polynucleotides are purified DNA molecules that stimulate skin repair, hydration, and collagen production. They work by helping your skin regenerate naturally, without altering your facial features.

Yes. Polynucleotides are clinically proven, biocompatible, and widely used in regenerative aesthetics. They are injected in small amounts and are suitable even for delicate areas such as the under-eyes.

Common treatment areas include under-eyes, face, neck, décolletage, and hands. They are especially effective where the skin is thin, dull, or showing early signs of aging.

You may notice improved hydration quickly, but the most visible changes, smoother texture, brighter skin, and improved elasticity, develop gradually over 2–6 weeks.

A course of 2–4 sessions is typically recommended for best results, spaced 2–3 weeks apart. Maintenance every 6–12 months helps prolong the rejuvenating effects.

Most clients find the treatment very tolerable. A topical numbing cream can be applied to ensure comfort, especially for sensitive areas like the under-eyes.

Downtime is minimal. You may experience slight redness or puffiness for a few hours, and mild swelling in treated areas for 1–2 days.

Absolutely. They pair beautifully with Hydrafacial, Microneedling, PRP, and Botox for enhanced skin quality and long-lasting rejuvenation.

Polynucleotides are ideal for anyone seeking smoother, brighter, healthier-looking skin, especially if you’ve noticed dullness, dehydration, crepey texture, or early aging.

Most clients enjoy results for 6–12 months, depending on skin condition, lifestyle, and the number of sessions completed.